Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | HTT | P42858 | 6/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CTSB | P07858 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11817125 | 0.83 | MAPT (0.64) | MAPTHTTPOLBLMNATDP1 | |
| SCHEMBL13483429 | 0.79 | MAPT (0.52) | MAPTHTTPOLBLMNATDP1 | |
| SCHEMBL5921938 | 0.79 | CTSB (0.61) | MAPTHTTPOLBLMNATDP1 | |
| SCHEMBL25201869 | 0.78 | ALDH1A1 (0.41) | MAPTHTTPOLBGAAHIPK2 | |
| SCHEMBL21155430 | 0.78 | ALDH1A1 (0.45) | MAPTHTTPOLBGAAHIPK2 | |
| SCHEMBL5656353 | 0.78 | MAPT (0.56) | MAPTHTTPOLBLMNATDP1 | |
| SCHEMBL3577339 | 0.76 | MAPT (0.52) | MAPTHTTPOLBLMNATDP1 | |
| SCHEMBL619318 | 0.76 | MAPT (0.52) | MAPTHTTPOLBLMNATDP1 | |
| SCHEMBL31451862 | 0.76 | MAPT (0.54) | MAPTHTTPOLBLMNATDP1 | |
| SCHEMBL1351778 | 0.76 | MAPT (0.56) | MAPTHTTPOLBLMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |