Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21155430 | 0.85 | ALDH1A1 (0.45) | ALDH1A1HTTMAPTGAARAB9A | |
| SCHEMBL29953514 | 0.78 | MAPT (0.52) | ALDH1A1HTTMAPTGAARAB9A | |
| SCHEMBL8568179 | 0.76 | ALDH1A1 (0.53) | ALDH1A1HTTMAPTGAARAB9A | |
| SCHEMBL171809 | 0.75 | HSD17B10 (0.52) | ALDH1A1HTTMAPTGAARAB9A | |
| SCHEMBL488895 | 0.75 | GPR35 (0.47) | ALDH1A1HTTMAPTGAARAB9A | |
| SCHEMBL30746531 | 0.74 | TDP1 (0.39) | ALDH1A1HTTGAAKMT2AMEN1 | |
| SCHEMBL20604640 | 0.74 | TDP1 (0.39) | ALDH1A1HTTGAAKMT2AMEN1 | |
| SCHEMBL8560647 | 0.74 | HTT (0.50) | ALDH1A1HTTMAPTGAAKMT2A | |
| SCHEMBL27546560 | 0.73 | KMT2A (0.49) | ALDH1A1HTTMAPTGAARAB9A | |
| Ammonia Solution, Strong SCHEMBL27551880 | 0.73 | HSD17B10 (0.50) | ALDH1A1HTTMAPTGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250025581-A1 | Medical Imaging of Glycogen Synthase Kinase-3 with a PET Probe | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH | 2025-01-23 | — | — | US | disclosed |
| EP-4433454-A2 | MEDICAL IMAGING OF GLYCOGEN SYNTHASE KINASE-3 WITH A PET PROBE | Mayo Foundation for Medical Education and Research (US) | 2024-09-25 | — | — | EP | disclosed |
| WO-2023091697-A2 | MEDICAL IMAGING OF GLYCOGEN SYNTHASE KINASE-3 WITH A PET PROBE | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2023-05-25 | — | — | WO | disclosed |
| CN-113717181-B | Host material, organic photoelectric device and display or lighting device | 浙江华显光电科技有限公司 | 2022-09-30 | — | — | CN | disclosed |
| CN-113817462-B | Host material, organic photoelectric device and display or lighting device | 浙江华显光电科技有限公司 | 2022-09-30 | — | — | CN | disclosed |
| CN-113817462-A | Host material, organic photoelectric device and display or lighting device | 浙江华显光电科技有限公司 | 2021-12-21 | — | — | CN | disclosed |
| CN-113717181-A | Host material, organic photoelectric device and display or lighting device | 浙江华显光电科技有限公司 | 2021-11-30 | — | — | CN | disclosed |
| CN-113444097-A | Tri-carbazole derivative, organic photoelectric device, and display or lighting device | 浙江华显光电科技有限公司 | 2021-09-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250025581-A1 | Medical Imaging of Glycogen Synthase Kinase-3 with a PET Probe | GYS2, GYS1, PKN3 | ALDH1A1 3548/4885HTT 1896/4885MAPT 2564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.