Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | FDPS | P14324 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | TTR | P02766 | 1/20 | 0.53 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.51 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.51 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.51 |
| ▸ | ABAT | P80404 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL481230 | 1.00 | ALDH1A1 (0.67) | ALDH1A1TSHRFDPSKDM4EAOX1 | |
| SCHEMBL286401 | 0.89 | ALDH1A1 (0.61) | ALDH1A1TSHRFDPSKDM4EAOX1 | |
| SCHEMBL31261976 | 0.89 | ALDH1A1 (0.61) | ALDH1A1TSHRFDPSKDM4EAOX1 | |
| SCHEMBL29965683 | 0.85 | ESRRA (0.63) | ALDH1A1TSHRFDPSAOX1TTR | |
| SCHEMBL28889415 | 0.85 | ESRRA (0.63) | ALDH1A1TSHRFDPSAOX1TTR | |
| SCHEMBL5607264 | 0.85 | AR (0.53) | ALDH1A1TSHRFDPSAOX1TTR | |
| SCHEMBL6899726 | 0.85 | ALDH1A1 (0.47) | ALDH1A1TSHRFDPSKDM4EAOX1 | |
| SCHEMBL16319639 | 0.84 | ALDH1A1 (0.51) | ALDH1A1TSHRFDPSAOX1TTR | |
| SCHEMBL2381821 | 0.83 | ESRRA (0.64) | ALDH1A1TSHRFDPSAOX1TTR | |
| SCHEMBL29445723 | 0.82 | XDH (0.54) | ALDH1A1TSHRFDPSAOX1TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |