Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.56 |
| ▸ | ABAT | P80404 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.56 |
| ▸ | FDPS | P14324 | 1/20 | 0.53 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 8/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.47 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.47 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31261976 | 1.00 | ALDH1A1 (0.61) | ALDH1A1TSHRTRIM24HPGDALDH5A1 | |
| SCHEMBL481230 | 0.89 | ALDH1A1 (0.67) | ALDH1A1TSHRTRIM24HPGDALDH5A1 | |
| SCHEMBL29953528 | 0.89 | ALDH1A1 (0.67) | ALDH1A1TSHRTRIM24HPGDALDH5A1 | |
| SCHEMBL16180271 | 0.83 | AR (0.51) | ALDH1A1TSHRTRIM24TRIM33AR | |
| SCHEMBL16954450 | 0.82 | AR (0.49) | ALDH1A1ARIMPDH2IMPDH1KDM4E | |
| SCHEMBL22031541 | 0.82 | ALDH1A1 (0.61) | ALDH1A1TSHRTRIM24HPGDALDH5A1 | |
| SCHEMBL15155225 | 0.82 | TRPA1 (0.56) | ALDH1A1ARIMPDH2IMPDH1KDM4E | |
| SCHEMBL28889415 | 0.82 | ESRRA (0.63) | ALDH1A1TSHRTRIM24HPGDALDH5A1 | |
| SCHEMBL29965683 | 0.82 | ESRRA (0.63) | ALDH1A1TSHRTRIM24HPGDALDH5A1 | |
| SCHEMBL5343920 | 0.82 | ALDH1A1 (0.53) | ALDH1A1TSHRTRIM24HPGDALDH5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119775164-A | Preparation method of 4-cyano-3-methoxybenzaldehyde | 浙江工业大学 | 2025-04-08 | — | — | CN | claimed |
| WO-2026107227-A1 | COMPOSITIONS COMPRISING USP1 INHIBITORS AND METHODS OF USING THE SAME | EIKON THERAPEUTICS, INC. (US) | 2026-05-21 | — | — | WO | disclosed |
| US-20250360141-A1 | PYRIDINE DERIVATIVES WITH N-LINKED CYCLIC SUBSTITUENTS AS cGAS INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2025-11-27 | — | — | US | disclosed |
| US-12433897-B2 | Pyridine derivatives with n-linked cyclic substituents as cGAS inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2025-10-07 | — | — | US | disclosed |
| CN-119775164-A | Preparation method of 4-cyano-3-methoxybenzaldehyde | 浙江工业大学 | 2025-04-08 | — | — | CN | disclosed |
| CN-119775164-A | Preparation method of 4-cyano-3-methoxybenzaldehyde | 浙江工业大学 | 2025-04-08 | — | — | CN | disclosed |
| CN-119775164-A | Preparation method of 4-cyano-3-methoxybenzaldehyde | 浙江工业大学 | 2025-04-08 | — | — | CN | disclosed |
| CN-119119062-A | Pyridine derivatives having N-linked cyclic substituents as cGAS inhibitors | 勃林格殷格翰国际有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-119119063-A | Pyridine derivatives having N-linked cyclic substituents as cGAS inhibitors | 勃林格殷格翰国际有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-118994148-A | Preparation method and intermediate of non-neridrone | 奥锐特药业股份有限公司 | 2024-11-22 | — | — | CN | disclosed |
| WO-2013090271-A1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | MERCK SHARP & DOHME CORP. (US) | 2013-06-20 | — | — | WO | disclosed |
| WO-2013028474-A1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | MERCK SHARP & DOHME CORP. (US) | 2013-02-28 | — | — | WO | disclosed |
| WO-2012058116-A1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | MERCK SHARP & DOHME CORP. (US) | 2012-05-03 | — | — | WO | disclosed |
| EP-2427444-A1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | Merck Sharp & Dohme Corp. (US) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010129379-A1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | MERCK SHARP & DOHME CORP. (US) | 2010-11-11 | — | — | WO | disclosed |
| US-20100286123-A1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | MERCK SHARP & DOHME LLC | 2010-11-11 | — | — | US | disclosed |
| WO-2008016811-A2 | AMINOPIPERIDINES AND REALTED COMPOUNDS | NEUROGEN CORPORATION (US) | 2008-02-07 | — | — | WO | disclosed |
| EP-1704161-A1 | HELIX 12 DIRECTED STEROIDAL PHARMACEUTICAL PRODUCTS | Endorecherche, Inc. (CA) | 2006-09-27 | — | — | EP | disclosed |
| US-20050250749-A1 | Helix 12 directed pharmaceutical products | ENDORECHERCHE, INC. | 2005-11-10 | — | — | US | disclosed |
| WO-2005066194-A1 | HELIX 12 DIRECTED STEROIDAL PHARMACEUTICAL PRODUCTS | ENDORECHERCHE, INC. (CA) | 2005-07-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250749-A1 | Helix 12 directed pharmaceutical products | SHBG, AR, NR5A1 | ALDH1A1 2314/4885TSHR 3672/4885TRIM24 950/4885 |
| US-20100286123-A1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | KCNJ11, KCNJ1, KCNJ2 | ALDH1A1 1376/4885TSHR 1257/4885TRIM24 2294/4885 |
| US-20250360141-A1 | PYRIDINE DERIVATIVES WITH N-LINKED CYCLIC SUBSTITUENTS AS cGAS INHIBITORS | CGAS, GLS2, GMPS | ALDH1A1 1206/4885TSHR 1727/4885TRIM24 3159/4885 |
| US-12433897-B2 | Pyridine derivatives with n-linked cyclic substituents as cGAS inhibitors | CGAS, GLS2, GMPS | ALDH1A1 1112/4885TSHR 1652/4885TRIM24 3136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.