Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | PRNP | P04156 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955281 | 0.88 | LMNA (0.77) | PRKDCMAPTLMNAALDH1A1HPGD | |
| SCHEMBL20563979 | 0.88 | PTGDR2 (0.58) | PRKDCMAPTLMNAALDH1A1HPGD | |
| SCHEMBL2556532 | 0.87 | ALDH1A1 (0.71) | PRKDCMAPTLMNAALDH1A1HPGD | |
| SCHEMBL11328128 | 0.82 | PTGDR2 (0.58) | PRKDCMAPTALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL29951681 | 0.82 | ALDH1A1 (0.77) | PRKDCMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL515642 | 0.82 | PRKDC (1.00) | PRKDCMAPTLMNAALDH1A1HPGD | |
| SCHEMBL24498697 | 0.81 | PTGDR2 (0.65) | PRKDCMAPTLMNAALDH1A1L3MBTL1 | |
| SCHEMBL14835649 | 0.81 | LMNA (0.87) | PRKDCMAPTLMNAALDH1A1HPGD | |
| SCHEMBL1620382 | 0.81 | LMNA (0.87) | PRKDCMAPTLMNAALDH1A1HPGD | |
| SCHEMBL29976495 | 0.80 | PRKDC (0.74) | PRKDCMAPTLMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |