Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.35 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.35 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.33 |
| ▸ | TUBB | P07437 | 3/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21711901 | 0.84 | ENPP2 (0.41) | ENPP2SLC6A2SLC6A4SLC6A3PDE10A | |
| SCHEMBL29954372 | 0.84 | ENPP2 (0.41) | ENPP2SLC6A2SLC6A4SLC6A3PDE10A | |
| SCHEMBL994085 | 0.80 | ENPP2 (0.41) | ENPP2ORAI1ORAI2ORAI3ALDH1A1 | |
| SCHEMBL15009942 | 0.78 | ENPP2 (0.39) | ENPP2PDE10AORAI1ORAI2ORAI3 | |
| SCHEMBL1054720 | 0.76 | ALDH1A1 (0.46) | SLC6A2SLC6A4SLC6A3PDE10AALDH1A1 | |
| SCHEMBL5748850 | 0.76 | ENPP2 (0.37) | ENPP2PDE10AORAI1ORAI2ORAI3 | |
| SCHEMBL10372181 | 0.75 | MAOB (0.43) | SLC6A2SLC6A4SLC6A3PDE10AALDH1A1 | |
| SCHEMBL30868926 | 0.74 | PDE10A (0.41) | ENPP2PDE10AALDH1A1MAPTTSHR | |
| SCHEMBL22445288 | 0.74 | UHRF1 (0.48) | UHRF1 | |
| SCHEMBL29951379 | 0.74 | UHRF1 (0.48) | UHRF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |