Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19004905 | 0.83 | SMPD3 (0.40) | MAOBSLC6A2SLC6A4SLC6A3SMPD3 | |
| SCHEMBL1054720 | 0.79 | ALDH1A1 (0.46) | SLC6A2SLC6A4SLC6A3SMN1; SMN2PDE10A | |
| SCHEMBL15132113 | 0.78 | MAOB (0.43) | MAOBFYNSLC22A6SLC22A8MEN1 | |
| SCHEMBL4128579 | 0.77 | UHRF1 (0.43) | SLC6A2SLC6A4SLC6A3PDE10AALDH1A1 | |
| SCHEMBL24816680 | 0.77 | MAOB (0.42) | MAOBFYNSLC22A6SLC22A8MEN1 | |
| SCHEMBL17143195 | 0.77 | MAOB (0.42) | MAOBSLC22A6SLC22A8MEN1RAB9A | |
| SCHEMBL28888359 | 0.77 | MAOB (0.42) | MAOBCHEK2SLC22A6SLC22A8MEN1 | |
| SCHEMBL29214455 | 0.77 | NOS3 (0.44) | MAOBCHEK2FYNAPP | |
| SCHEMBL107611 | 0.76 | IDO1 (0.40) | SLC6A2SLC6A4SLC6A3KMT2AAPP | |
| SCHEMBL29953594 | 0.75 | ENPP2 (0.41) | SLC6A2SLC6A4SLC6A3SMPD3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0390842-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1990-10-10 | — | — | EP | disclosed |
| WO-1989005299-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1989-06-15 | — | — | WO | disclosed |