Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.65 |
| ▸ | ESR1 | P03372 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | APEX1 | P27695 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | BRD4 | O60885 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PTPRC | P08575 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16291648 | 0.87 | BRD4 (0.53) | TP53ESR1POLBAPEX1MAPK1 | |
| SCHEMBL11281072 | 0.83 | TP53 (0.61) | TP53ESR1POLBAPEX1MAPK1 | |
| SCHEMBL6814873 | 0.83 | TP53 (0.65) | TP53ESR1POLBAPEX1MAPK1 | |
| SCHEMBL15330025 | 0.83 | L3MBTL1 (0.65) | TP53ESR1POLBAPEX1MAPK1 | |
| SCHEMBL2557126 | 0.83 | TP53 (0.61) | TP53ESR1POLBAPEX1MAPK1 | |
| SCHEMBL29953609 | 0.82 | ESR1 (0.63) | TP53ESR1POLBAPEX1MAPK1 | |
| SCHEMBL2559247 | 0.82 | TDP1 (0.60) | TP53ESR1POLBAPEX1MAPK1 | |
| SCHEMBL2559881 | 0.82 | ESR1 (0.63) | TP53ESR1POLBAPEX1MAPK1 | |
| SCHEMBL30117303 | 0.80 | TDP1 (0.56) | TP53ESR1POLBAPEX1MAPK1 | |
| SCHEMBL11617753 | 0.79 | L3MBTL1 (0.50) | TP53ESR1POLBAPEX1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004012656-A2 | THIOPHENE AND FURAN DERIVATIVES AS PROSTAGLANDIN AGONISTS AND USE THEREOF | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2004-02-12 | — | — | WO | disclosed |