Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CACNA1I | Q9P0X4 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27731632 | 0.82 | HTT (0.41) | SMN1; SMN2KMT2ALMNATSHRKDM4E | |
| SCHEMBL29957137 | 0.82 | KDM4E (0.42) | SMN1; SMN2MEN1KMT2ANPC1LMNA | |
| SCHEMBL2561710 | 0.79 | PKM (0.50) | SMN1; SMN2MEN1KMT2ATSHRKDM4E | |
| SCHEMBL2556051 | 0.79 | ALDH1A1 (0.46) | SMN1; SMN2MEN1KMT2ATSHRKDM4E | |
| SCHEMBL2558914 | 0.79 | KDM4E (0.68) | SMN1; SMN2MEN1KMT2ALMNAKDM4E | |
| SCHEMBL2561158 | 0.78 | TLR9 (0.39) | SMN1; SMN2NPC1KDM4EALDH1A1TDP1 | |
| SCHEMBL29951726 | 0.78 | HTT (0.39) | SMN1; SMN2LMNAALOX15TSHRKDM4E | |
| SCHEMBL2560665 | 0.78 | HTT (0.39) | SMN1; SMN2KMT2ALMNATSHRKDM4E | |
| SCHEMBL15331209 | 0.78 | ALDH1A1 (0.49) | SMN1; SMN2MEN1KMT2ALMNATSHR | |
| SCHEMBL2554918 | 0.78 | TLR9 (0.38) | SMN1; SMN2MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |