Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CTSK | P43235 | 3/20 | 0.37 |
| ▸ | CTSB | P07858 | 2/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2557343 | 0.85 | MAPT (0.47) | HTTTLR9TLR8TLR7ALDH1A1 | |
| SCHEMBL2560665 | 0.85 | HTT (0.39) | HTTALDH1A1TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL29954597 | 0.83 | HPGD (0.41) | ALDH1A1CTSKCTSBCTSSKDM4E | |
| SCHEMBL27731632 | 0.83 | HTT (0.41) | HTTALDH1A1TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL2556051 | 0.80 | ALDH1A1 (0.46) | HTTTLR9TLR8TLR7ALDH1A1 | |
| SCHEMBL2555207 | 0.79 | HTT (0.37) | HTTALDH1A1KDM4ESMN1; SMN2DRD4 | |
| SCHEMBL15331209 | 0.79 | ALDH1A1 (0.49) | HTTALDH1A1TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL2561158 | 0.79 | TLR9 (0.39) | HTTTLR9TLR8TLR7ALDH1A1 | |
| SCHEMBL29953615 | 0.78 | SMN1; SMN2 (0.41) | HTTTLR9TLR8TLR7ALDH1A1 | |
| SCHEMBL29955822 | 0.78 | SIGMAR1 (0.44) | HTTALDH1A1KDM4ESMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |