Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955671 | 0.88 | KMT2A (0.43) | KMT2AMETERN1NPC1ALDH1A1 | |
| SCHEMBL29957196 | 0.79 | KMT2A (0.56) | KMT2ALRRK2CYP2A6IMPDH2 | |
| SCHEMBL2882516 | 0.78 | AXL (0.41) | METNPC1ALDH1A1RAB9AMAPT | |
| SCHEMBL14158703 | 0.78 | MET (0.40) | KMT2AMETNPC1ALDH1A1RAB9A | |
| SCHEMBL857522 | 0.78 | LRRK2 (0.53) | KMT2ACYP3A4LRRK2CYP2A6IMPDH2 | |
| SCHEMBL4530465 | 0.78 | LRRK2 (0.53) | KMT2ACYP3A4LRRK2CYP2A6IMPDH2 | |
| SCHEMBL858934 | 0.75 | LRRK2 (0.50) | KMT2AMETALDH1A1MEN1TDP1 | |
| SCHEMBL17843962 | 0.74 | KMT2A (0.51) | KMT2AALDH1A1LRRK2CYP2A6 | |
| SCHEMBL29952362 | 0.74 | KMT2A (0.51) | KMT2AERN1LRRK2CYP2A6IMPDH2 | |
| SCHEMBL29958099 | 0.74 | KMT2A (0.51) | KMT2AERN1NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |