SCHEMBL29953667

SCHEMBL29953667

O=CCCc1ccncn1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.35
P2RX7 Q99572 1/20 0.35
KCNH3 Q9ULD8 1/20 0.33
CYP1B1 Q16678 1/20 0.32
FAAH O00519 1/20 0.32
NAMPT P43490 1/20 0.31
PKM P14618 1/20 0.30
HTT P42858 1/20 0.30
GFER P55789 1/20 0.30
KMT2A Q03164 1/20 0.30
GABRA1 P14867 1/20 0.30
GABRG2 P18507 1/20 0.30
GABRB3 P28472 1/20 0.30
GABRA5 P31644 1/20 0.30
GABRA3 P34903 1/20 0.30
GABRA2 P47869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL348051 1.00 HSP90AA1 (0.35) HSP90AA1P2RX7KCNH3CYP1B1FAAH
SCHEMBL5882639 0.89 P2RX7 (0.33) HSP90AA1P2RX7KCNH3CYP1B1FAAH
SCHEMBL8191782 0.79 P2RX7 (0.36) HSP90AA1P2RX7KCNH3CYP1B1NAMPT
SCHEMBL4661605 0.79
SCHEMBL16399930 0.77
SCHEMBL27413848 0.76 P2RX7 (0.33) HSP90AA1P2RX7KCNH3CYP1B1NAMPT
SCHEMBL8185282 0.74 KCNH3 (0.42) HSP90AA1P2RX7KCNH3NAMPT
Hydrochloric Acid SCHEMBL27536901 0.74 P2RX7 (0.32) HSP90AA1P2RX7KCNH3NAMPTHTT
SCHEMBL349709 0.73 HRH1 (0.55)
SCHEMBL5040815 0.73 HSP90AA1 (0.37) HSP90AA1P2RX7KCNH3CYP1B1NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed