Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NOS3 | P29474 | 1/20 | 0.48 |
| ▸ | NOS1 | P29475 | 1/20 | 0.48 |
| ▸ | NOS2 | P35228 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TLR4 | O00206 | 1/20 | 0.48 |
| ▸ | TLR2 | O60603 | 1/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.44 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.44 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.44 |
| ▸ | CYP27B1 | O15528 | 1/20 | 0.43 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12420271 | 0.85 | ENPP2 (0.54) | ENPP2APPCYP4F2CYP4A11F2 | |
| SCHEMBL22315 | 0.85 | CYP4F2 (0.58) | ENPP2MEN1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL29953375 | 0.85 | LTA4H (0.49) | ENPP2SLC2A1SLC2A4F2 | |
| SCHEMBL17236537 | 0.84 | APP (0.53) | ENPP2MEN1KMT2AAPPCYP4F2 | |
| SCHEMBL29954250 | 0.84 | MAPK1 (0.53) | ENPP2MAPK1GPR132 | |
| SCHEMBL16687440 | 0.83 | ENPP2 (0.56) | ENPP2SMN1; SMN2APPCYP4F2CYP4A11 | |
| SCHEMBL23988 | 0.81 | NR4A2 (0.58) | ENPP2SMN1; SMN2MEN1MAPK1HTT | |
| SCHEMBL29952469 | 0.81 | MAOB (0.62) | ENPP2APPF2 | |
| SCHEMBL459524 | 0.81 | MAOB (0.60) | ENPP2SMN1; SMN2MEN1KMT2ANR4A2 | |
| SCHEMBL22563 | 0.81 | ENPP2 (0.67) | ENPP2TLR4TLR2APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |