Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2916070 | 0.92 | KDM1A (0.38) | KDM1AHTTL3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL16687404 | 0.86 | L3MBTL1 (0.38) | KDM1AHTTL3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL29417474 | 0.86 | L3MBTL1 (0.38) | KDM1AHTTL3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL2914756 | 0.84 | PDE4D (0.44) | L3MBTL1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL28697955 | 0.81 | PTPN1 (0.30) | — | |
| SCHEMBL4599515 | 0.81 | TDP1 (0.38) | KDM1AHTTL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL4886560 | 0.78 | KDM1A (0.39) | KDM1AHTTL3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL789623 | 0.78 | ENPP2 (0.43) | KDM1AHTTMAPK1TUBB1RAB9A | |
| SCHEMBL29408115 | 0.78 | ENPP2 (0.43) | KDM1AHTTMAPK1TUBB1RAB9A | |
| SCHEMBL29957476 | 0.76 | LIPE (0.61) | KDM1AL3MBTL1MAPTMAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |