Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 6/20 | 0.49 |
| ▸ | NOS3 | P29474 | 3/20 | 0.49 |
| ▸ | NOS1 | P29475 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29950665 | 0.84 | NOS2 (0.44) | NOS2KMT2AESR1ESR2EPHX2 | |
| SCHEMBL1274306 | 0.83 | ATM (0.50) | CA12CA7CA9CA14MEN1 | |
| SCHEMBL5888360 | 0.80 | PTPRB (0.58) | NOS2NOS3NOS1TSHRCA12 | |
| SCHEMBL29956929 | 0.79 | ACACB (0.48) | MEN1KMT2AESR1ESR2PPARG | |
| SCHEMBL1678477 | 0.78 | TSHR (0.55) | NOS2NOS3NOS1TSHRCA12 | |
| SCHEMBL180106 | 0.78 | NOS2 (0.52) | NOS2NOS3NOS1TSHRCA12 | |
| SCHEMBL180105 | 0.78 | NOS2 (0.52) | NOS2NOS3NOS1TSHRCA12 | |
| SCHEMBL7406014 | 0.78 | TSHR (0.55) | NOS2NOS3NOS1TSHRCA12 | |
| SCHEMBL29956201 | 0.77 | TACR1 (0.41) | NOS2NOS3NOS1TSHRMEN1 | |
| SCHEMBL2833 | 0.77 | NOS2 (0.51) | NOS2NOS3NOS1TSHRCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |