Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953707 | 0.84 | NOS2 (0.49) | NOS2PPARGESR1ESR2KMT2A | |
| SCHEMBL1274306 | 0.83 | ATM (0.50) | ALDH1A1KMT2APOLBL3MBTL1 | |
| SCHEMBL15180970 | 0.80 | PTPRB (0.58) | NOS2PPARGPPARAALDH1A1ESR1 | |
| SCHEMBL29956929 | 0.79 | ACACB (0.48) | PPARGPPARAALDH1A1ESR1ESR2 | |
| SCHEMBL25241069 | 0.78 | NOS2 (0.50) | NOS2PPARGPPARAALDH1A1ESR1 | |
| SCHEMBL163965 | 0.78 | NOS2 (0.47) | NOS2PPARGPPARAALDH1A1ESR1 | |
| SCHEMBL7597924 | 0.78 | FPR2 (0.49) | NOS2PPARGPPARAALDH1A1ESR1 | |
| SCHEMBL13572956 | 0.78 | FPR2 (0.49) | NOS2PPARGPPARAALDH1A1ESR1 | |
| SCHEMBL20502249 | 0.78 | NOS2 (0.47) | NOS2PPARGPPARAALDH1A1ESR1 | |
| SCHEMBL6575200 | 0.78 | FPR2 (0.49) | NOS2PPARGPPARAALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |