Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | KDM4B | O94953 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 6/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.36 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18209362 | 0.77 | ALDH1A1 (0.50) | LMNAKDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL2172238 | 0.77 | KDM4A (0.42) | LMNAKDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL7090852 | 0.76 | MYC (0.57) | LMNAMYCHCRTR1HCRTR2KMT2A | |
| SCHEMBL29551359 | 0.76 | MYC (0.57) | LMNAMYCHCRTR1HCRTR2KMT2A | |
| SCHEMBL2650286 | 0.75 | MAPK1 (0.51) | LMNAHCRTR1HCRTR2KMT2AKDM4E | |
| SCHEMBL21407089 | 0.75 | ALDH1A1 (0.48) | LMNAKDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL21407080 | 0.75 | NOTUM (0.43) | LMNAKDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL28300532 | 0.74 | MAPK1 (0.50) | LMNAKDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL16544035 | 0.73 | HCRTR2 (0.49) | LMNAMYCHCRTR1HCRTR2KMT2A | |
| SCHEMBL952863 | 0.73 | NOTUM (0.48) | LMNAKDM4AKDM4BKDM5CKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |