Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | KDM4B | O94953 | 1/20 | 0.42 |
| ▸ | KDM5C | P41229 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21407080 | 0.79 | NOTUM (0.43) | NOTUMADORA2AKDM4AKDM4BKDM5C | |
| SCHEMBL28300532 | 0.78 | MAPK1 (0.50) | NOTUMADORA2AKDM4AKDM4BKDM5C | |
| SCHEMBL1924873 | 0.77 | ADORA2A (0.45) | NOTUMADORA2AKDM4AKDM4BKDM5C | |
| SCHEMBL12613954 | 0.77 | KDM4A (0.42) | NOTUMADORA2AKDM4AKDM4BKDM5C | |
| SCHEMBL8671607 | 0.77 | KDM4A (0.42) | NOTUMADORA2AKDM4AKDM4BKDM5C | |
| SCHEMBL2172238 | 0.77 | KDM4A (0.42) | NOTUMADORA2AKDM4AKDM4BKDM5C | |
| SCHEMBL20394404 | 0.77 | ADORA2A (0.45) | NOTUMADORA2AKDM4AKDM4BKDM5C | |
| SCHEMBL18209362 | 0.77 | ALDH1A1 (0.50) | NOTUMADORA2AKDM4AKDM4BKDM5C | |
| SCHEMBL22396743 | 0.77 | NOTUM (0.41) | NOTUMADORA2AKDM4AKDM4BKDM5C | |
| SCHEMBL639253 | 0.76 | HSD11B1 (0.35) | ADORA2ALMNAMALT1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110407813-B | Pyrazole oxime compound containing 1- (3-chloropyridine-2-yl) pyrazole structure and preparation method and application thereof | 南通大学 | 2021-07-06 | — | — | CN | claimed |
| CN-110407831-B | Preparation and application of pyrazole oxime ester derivative containing N- (3-chloropyridine-2-yl) pyrazole structure | 南通大学 | 2021-04-23 | — | — | CN | claimed |
| CN-110122495-A | Compound containing 1- (3- chloro-2-pyridyl) -1 hydrogen-pyrazoles active fragment is preparing the application in fungicide | 马毅辉 | 2019-08-16 | — | — | CN | claimed |
| US-11284623-B2 | Pesticidal mixtures | BASF CORPORATION (US) | 2022-03-29 | — | — | US | disclosed |
| CN-110407813-B | Pyrazole oxime compound containing 1- (3-chloropyridine-2-yl) pyrazole structure and preparation method and application thereof | 南通大学 | 2021-07-06 | — | — | CN | disclosed |
| CN-110407813-B | Pyrazole oxime compound containing 1- (3-chloropyridine-2-yl) pyrazole structure and preparation method and application thereof | 南通大学 | 2021-07-06 | — | — | CN | disclosed |
| CN-110407813-B | Pyrazole oxime compound containing 1- (3-chloropyridine-2-yl) pyrazole structure and preparation method and application thereof | 南通大学 | 2021-07-06 | — | — | CN | disclosed |
| CN-110407831-B | Preparation and application of pyrazole oxime ester derivative containing N- (3-chloropyridine-2-yl) pyrazole structure | 南通大学 | 2021-04-23 | — | — | CN | disclosed |
| CN-110407831-B | Preparation and application of pyrazole oxime ester derivative containing N- (3-chloropyridine-2-yl) pyrazole structure | 南通大学 | 2021-04-23 | — | — | CN | disclosed |
| CN-110407831-B | Preparation and application of pyrazole oxime ester derivative containing N- (3-chloropyridine-2-yl) pyrazole structure | 南通大学 | 2021-04-23 | — | — | CN | disclosed |
| CN-110122495-A | Compound containing 1- (3- chloro-2-pyridyl) -1 hydrogen-pyrazoles active fragment is preparing the application in fungicide | 马毅辉 | 2019-08-16 | — | — | CN | disclosed |
| EP-2251336-A1 | Hydrazide compounds as intermediates of pesticides | Sumitomo Chemical Company, Limited (JP) | 2010-11-17 | — | — | EP | disclosed |
| US-20090181956-A1 | Hydrazide Compound and Pesticidal Use of the Same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-07-16 | — | — | US | disclosed |
| US-20090181956-A1 | Hydrazide Compound and Pesticidal Use of the Same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-07-16 | — | — | US | disclosed |
| CN-101287721-A | Hydrazide compound and pesticidal use of the same | SUMITOMO CHEMICAL CO (JP) | 2008-10-15 | — | — | CN | disclosed |
| EP-1937664-A1 | HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | Sumitomo Chemical Company, Limited (JP) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007043677-A9 | HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | SUMITOMO CHEMICAL CO (JP) | 2007-06-07 | — | — | WO | disclosed |
| WO-2007043677-A9 | HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | SUMITOMO CHEMICAL CO (JP) | 2007-06-07 | — | — | WO | disclosed |
| WO-2007043677-A1 | HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-04-19 | — | — | WO | disclosed |
| WO-2007043677-A1 | HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-04-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181956-A1 | Hydrazide Compound and Pesticidal Use of the Same | ACHE, DDT, CAT | NOTUM 520/4885ADORA2A 3986/4885KDM4A 2310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.