SCHEMBL2172238

SCHEMBL2172238

Cc1cccnc1-n1cccn1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4A O75164 1/20 0.42
KDM4B O94953 1/20 0.42
KDM5C P41229 1/20 0.42
KDM5B Q9UGL1 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
NOS3 P29474 1/20 0.41
NOS1 P29475 1/20 0.41
NOS2 P35228 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
HCRTR1 O43613 1/20 0.40
HCRTR2 O43614 1/20 0.40
NOTUM Q6P988 1/20 0.40
LMNA P02545 1/20 0.39
CYP2C9 P11712 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
GRM4 Q14833 1/20 0.39
NPC1 O15118 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28300532 0.78 MAPK1 (0.50) KDM4AKDM4BKDM5CKDM5BMEN1
SCHEMBL1924873 0.77 ADORA2A (0.45) KDM4AKDM4BKDM5CKDM5BMEN1
SCHEMBL8671607 0.77 KDM4A (0.42) KDM4AKDM4BKDM5CKDM5BNPSR1
SCHEMBL952863 0.77 NOTUM (0.48) KDM4AKDM4BKDM5CKDM5BMEN1
SCHEMBL12613954 0.77 KDM4A (0.42) KDM4AKDM4BKDM5CKDM5BNPSR1
SCHEMBL18209362 0.77 ALDH1A1 (0.50) KDM4AKDM4BKDM5CKDM5BMEN1
SCHEMBL20394404 0.77 ADORA2A (0.45) KDM4AKDM4BKDM5CKDM5BMEN1
SCHEMBL21571842 0.77 KDM4A (0.39) KDM4AKDM4BKDM5CKDM5BMEN1
SCHEMBL29953726 0.77 LMNA (0.40) KDM4AKDM4BKDM5CKDM5BMEN1
SCHEMBL17855887 0.76 KDM4A (0.41) KDM4AKDM4BKDM5CKDM5BMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4328232-A1 ELECTROCHEMICAL BIOSENSOR, OR SENSING MEMBRANE FOR ELECTROCHEMICAL BIOSENSOR CONTAINING TRANSITION METAL COMPLEX OR OXIDATION-REDUCTION POLYMER I-SENS, INC. (KR) 2024-02-28 EP disclosed
EP-3807266-A1 PYRAZOLE DERIVATIVES AS MALT1 INHIBITORS Janssen Pharmaceutica N.V. (BE) 2021-04-21 EP disclosed
WO-2019243964-A1 PYRAZOLE DERIVATIVES AS MALT1 INHIBITORS JANSSEN PHARMACEUTICA NV (BE) 2019-12-26 WO disclosed
US-20130281455-A1 Phenylpyri(mi)dinylazoles BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-10-24 US disclosed
US-20110183978-A1 Phenylpyri(mi)dinylazoles BAYER CROPSCIENCE AG (DE) 2011-07-28 US disclosed
US-7968573-B2 Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-28 US disclosed
US-20110071291-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME IKEGAMI HIROSHI 2011-03-24 US disclosed
US-7867949-B2 Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-11 US disclosed
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-07-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130281455-A1 Phenylpyri(mi)dinylazoles PIR, PIN4, PNN KDM4A 1423/4885KDM4B 669/4885KDM5C 1460/4885
US-20110183978-A1 Phenylpyri(mi)dinylazoles PIR, PIN4, PNN KDM4A 1423/4885KDM4B 669/4885KDM5C 1460/4885
US-20110071291-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME ACHE, H1-2, H1-0 KDM4A 1168/4885KDM4B 836/4885KDM5C 1812/4885
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same ACHE, DDT, CAT KDM4A 2310/4885KDM4B 1787/4885KDM5C 2943/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.