Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953750 | 0.87 | CREBBP (0.55) | ALDH1A1MEN1KMT2AL3MBTL1HTT | |
| SCHEMBL30708201 | 0.82 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL8644052 | 0.79 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2AHPGDL3MBTL1 | |
| SCHEMBL29951426 | 0.78 | HPGD (0.60) | ALDH1A1MEN1KMT2AHPGDL3MBTL1 | |
| SCHEMBL29952081 | 0.77 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2AHPGDL3MBTL1 | |
| SCHEMBL24939470 | 0.76 | MEN1 (0.55) | ALDH1A1MEN1KMT2AHPGDGAA | |
| SCHEMBL29179662 | 0.76 | MEN1 (0.55) | ALDH1A1MEN1KMT2AHPGDGAA | |
| SCHEMBL6342125 | 0.76 | ALDH1A1 (0.71) | ALDH1A1MEN1KMT2AHPGDL3MBTL1 | |
| SCHEMBL29951914 | 0.76 | HPGD (0.61) | ALDH1A1MEN1KMT2AHPGDL3MBTL1 | |
| SCHEMBL29956047 | 0.76 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2AHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |