Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.43 |
| ▸ | ABAT | P80404 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7684154 | 0.86 | KDM4E (0.54) | RAB9APOLBNPC1MAPTKDM4E | |
| SCHEMBL29957610 | 0.86 | KDM4E (0.54) | RAB9APOLBNPC1MAPTKDM4E | |
| SCHEMBL7535750 | 0.82 | RAB9A (0.52) | RAB9APOLBNPC1MAPTKDM4E | |
| SCHEMBL7013927 | 0.82 | ALDH1A1 (0.52) | RAB9APOLBNPC1MAPTKDM4E | |
| SCHEMBL618118 | 0.81 | CA1 (0.54) | RAB9APOLBNPC1MAPTKDM4E | |
| SCHEMBL7058277 | 0.81 | CA1 (0.54) | RAB9APOLBNPC1MAPTKDM4E | |
| SCHEMBL6108998 | 0.81 | HDAC1 (0.55) | RAB9APOLBNPC1MAPTKDM4E | |
| SCHEMBL7061559 | 0.81 | CA1 (0.55) | RAB9APOLBNPC1MAPTKDM4E | |
| SCHEMBL21428871 | 0.80 | MAPT (0.56) | RAB9APOLBNPC1MAPTKDM4E | |
| SCHEMBL29953591 | 0.79 | KDM4E (0.57) | RAB9AKDM4EPTGS2ALDH1A1AOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |