Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 6/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | LPL | P06858 | 2/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 4/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 4/20 | 0.40 |
| ▸ | PRMT8 | Q9NR22 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952628 | 0.95 | ENPP2 (0.49) | ENPP2EPHX1LPLLIPGCARM1 | |
| SCHEMBL29954386 | 0.87 | ENPP2 (0.46) | ENPP2EPHX1LPLLIPGCARM1 | |
| SCHEMBL29952340 | 0.81 | ENPP2 (0.44) | ENPP2EPHX1LPLLIPGCARM1 | |
| SCHEMBL29953735 | 0.80 | LPL (0.42) | ENPP2LPLLIPGCARM1PRMT6 | |
| SCHEMBL4961595 | 0.78 | SLC6A2 (0.46) | CARM1PRMT6PRMT8SLC6A2HTR2A | |
| SCHEMBL18616136 | 0.77 | OPRM1 (0.49) | ENPP2SLC6A2HTR2AHTR2CSLC6A4 | |
| SCHEMBL29951790 | 0.76 | ENPP2 (0.47) | ENPP2EPHX1LPLLIPG | |
| SCHEMBL18616222 | 0.76 | CARM1 (0.59) | CARM1PRMT6PRMT8SLC6A2SLC6A4 | |
| SCHEMBL10269521 | 0.76 | LPL (0.41) | ENPP2LPLLIPGCARM1PRMT6 | |
| SCHEMBL2557986 | 0.75 | ENPP2 (0.45) | ENPP2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |