Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.35 |
| ▸ | PARP1 | P09874 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | CTSV | O60911 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955797 | 0.90 | KDM4E (0.38) | KDM4EMAPTPTGS2PARP1ALDH1A1 | |
| SCHEMBL15331672 | 0.90 | PARP1 (0.36) | KDM4EMAPTPTGS2PARP1MAPK14 | |
| SCHEMBL2559858 | 0.89 | GPR17 (0.35) | MAPTPARP1 | |
| SCHEMBL2559831 | 0.88 | PTGS2 (0.34) | MAPTPTGS2PARP1 | |
| SCHEMBL29951490 | 0.86 | PARP1 (0.43) | PTGS2PARP1LMNAMAPK14TNKS2 | |
| SCHEMBL15331326 | 0.86 | MAPK13 (0.38) | KDM4EPTGS2PARP1MAPK14TNKS2 | |
| SCHEMBL29957654 | 0.84 | ALDH1A1 (0.39) | MAPTALDH1A1LMNAMAPK14TNKS2 | |
| SCHEMBL2559317 | 0.84 | PIM1 (0.37) | KDM4EMAPTPTGS2PARP1ALDH1A1 | |
| SCHEMBL2558139 | 0.82 | KDM4E (0.33) | KDM4EMAPTPTGS2PARP1ALDH1A1 | |
| SCHEMBL2558538 | 0.81 | PTGS2 (0.36) | PTGS2ALDH1A1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |