Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.80 |
| ▸ | RAB9A | P51151 | 1/20 | 0.80 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957481 | 0.91 | RAB9A (0.66) | KDM4ERAB9APTGS2LMNAALDH1A1 | |
| SCHEMBL2557701 | 0.89 | KDM4E (0.78) | KDM4ERAB9ALMNAALDH1A1KMT2A | |
| SCHEMBL29956422 | 0.84 | KDM4E (0.58) | KDM4ERAB9ALMNAALDH1A1KMT2A | |
| SCHEMBL29952430 | 0.83 | RAB9A (0.72) | KDM4ERAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL2554953 | 0.82 | KDM4E (0.71) | KDM4ERAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL15331114 | 0.82 | KDM4E (0.67) | KDM4ERAB9APTGS2LMNAALDH1A1 | |
| SCHEMBL29958222 | 0.81 | PTGDR2 (0.56) | KDM4ERAB9ALMNAALDH1A1KMT2A | |
| SCHEMBL2554836 | 0.81 | KDM4E (0.69) | KDM4ERAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL2556788 | 0.80 | RAB9A (0.64) | KDM4ERAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL29957515 | 0.80 | ALDH1A1 (0.62) | KDM4ERAB9ALMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |