Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953963 | 0.91 | KDM4E (0.80) | RAB9AKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL2556062 | 0.89 | RAB9A (0.63) | RAB9AKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL29957035 | 0.83 | ALDH1A1 (0.60) | RAB9AKDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL15331330 | 0.82 | ALDH1A1 (0.58) | RAB9AKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL2559590 | 0.82 | RAB9A (0.55) | RAB9AKDM4EALDH1A1KMT2APTGS2 | |
| SCHEMBL29958222 | 0.81 | PTGDR2 (0.56) | RAB9AKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL15332397 | 0.81 | KDM4E (0.56) | RAB9AKDM4EALDH1A1MAPTTRIM24 | |
| SCHEMBL2561319 | 0.80 | RAB9A (0.52) | RAB9AKDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL7840901 | 0.79 | ALDH1A1 (0.61) | RAB9AKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL2558788 | 0.79 | ALDH1A1 (0.61) | RAB9AKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |