Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956240 | 0.96 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1TSHRTP53CYP3A4 | |
| SCHEMBL29957977 | 0.83 | RAB9A (0.54) | SMN1; SMN2ALDH1A1TSHRTP53MAPT | |
| SCHEMBL17957130 | 0.82 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1TSHRTP53CYP3A4 | |
| SCHEMBL19384405 | 0.79 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1TSHRTP53CYP3A4 | |
| SCHEMBL1442839 | 0.79 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1TSHRTP53CYP3A4 | |
| SCHEMBL1442836 | 0.79 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1TSHRTP53CYP3A4 | |
| SCHEMBL12819945 | 0.79 | RAB9A (0.53) | SMN1; SMN2ALDH1A1TSHRTP53CYP3A4 | |
| SCHEMBL12818254 | 0.79 | RAB9A (0.53) | SMN1; SMN2ALDH1A1TSHRTP53CYP3A4 | |
| SCHEMBL29952782 | 0.79 | RAB9A (0.56) | SMN1; SMN2ALDH1A1TSHRTP53MAPT | |
| SCHEMBL27028554 | 0.79 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1TSHRTP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |