Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | IGF1R | P08069 | 2/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | INSR | P06213 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.43 |
| ▸ | EPHA4 | P54764 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26968756 | 0.83 | ALDH1A1 (0.77) | ALDH1A1SMN1; SMN2TP53CYP3A4TSHR | |
| SCHEMBL13948483 | 0.83 | ALDH1A1 (0.77) | ALDH1A1SMN1; SMN2TP53CYP3A4TSHR | |
| SCHEMBL1442839 | 0.82 | SMN1; SMN2 (0.53) | ALDH1A1RAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL12818254 | 0.82 | RAB9A (0.53) | ALDH1A1RAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL19384405 | 0.82 | SMN1; SMN2 (0.53) | ALDH1A1RAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL1442836 | 0.82 | SMN1; SMN2 (0.53) | ALDH1A1RAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL12819945 | 0.82 | RAB9A (0.53) | ALDH1A1RAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL17957130 | 0.82 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2TP53CYP3A4TSHR | |
| SCHEMBL3025476 | 0.81 | RAB9A (0.54) | ALDH1A1RAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL15650478 | 0.81 | RAB9A (0.54) | ALDH1A1RAB9ANPC1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240182475-A1 | METHODS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH HYPERMINERALIZATION | Université de Lausanne (CH) | 2024-06-06 | — | — | US | disclosed |
| EP-4308117-A1 | METHODS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH HYPERMINERALIZATION | Université de Lausanne (CH) | 2024-01-24 | — | — | EP | disclosed |
| WO-2022194953-A1 | METHODS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH HYPERMINERALIZATION | Université de Lausanne (CH) | 2022-09-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240182475-A1 | METHODS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH HYPERMINERALIZATION | CTH, CBS, GAA | ALDH1A1 2316/4885RAB9A 3925/4885NPC1 2791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.