Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.33 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.33 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.33 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.33 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.33 |
| ▸ | UBE2N | P61088 | 1/20 | 0.33 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2657700 | 0.79 | ENPP2 (0.39) | ENPP2IKBKBG6PDORAI1ORAI2 | |
| SCHEMBL29952035 | 0.75 | CCR1 (0.35) | — | |
| SCHEMBL29953746 | 0.74 | ENPP2 (0.38) | ENPP2DYRK1AIKBKBMAPK1L3MBTL1 | |
| SCHEMBL29955425 | 0.74 | ALDH1A1 (0.38) | ENPP2DYRK1AKMT2AKMOGAK | |
| SCHEMBL1662248 | 0.74 | DYRK1A (0.40) | CYP17A1CYP19A1CYP11B1CYP11B2DYRK1A | |
| SCHEMBL30320423 | 0.74 | DYRK1A (0.40) | CYP17A1CYP19A1CYP11B1CYP11B2DYRK1A | |
| SCHEMBL4704071 | 0.73 | ENPP2 (0.50) | ENPP2MAPK1MAPTKMT2AORAI1 | |
| SCHEMBL29954565 | 0.73 | ENPP2 (0.50) | ENPP2MAPK1MAPTKMT2AORAI1 | |
| SCHEMBL23624007 | 0.72 | HASPIN (0.46) | CYP17A1CYP19A1CYP11B1CYP11B2DYRK1A | |
| SCHEMBL3105493 | 0.72 | DYRK1A (0.42) | CYP17A1CYP19A1CYP11B1CYP11B2DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |