Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15329462 | 0.87 | PTGS2 (0.45) | CA1CA2ALDH1A1LMNAPTGS2 | |
| SCHEMBL15331430 | 0.85 | SMN1; SMN2 (0.41) | CA1CA2ALDH1A1LMNAPTGS2 | |
| SCHEMBL15330647 | 0.84 | ALDH1A1 (0.46) | ALDH1A1LMNAPTGS2MEN1MAPT | |
| SCHEMBL15331788 | 0.84 | SMN1; SMN2 (0.47) | ALDH1A1LMNAPTGS2MEN1MAPT | |
| SCHEMBL2563069 | 0.84 | MAPK14 (0.41) | ALDH1A1PTGS2MAPTKMT2APOLB | |
| SCHEMBL15332946 | 0.83 | TDP2 (0.40) | ALDH1A1MAPTMAPK1HTTPOLB | |
| SCHEMBL15332163 | 0.82 | CYP1A2 (0.45) | ALDH1A1LMNAMEN1MAPTKMT2A | |
| SCHEMBL15331899 | 0.82 | ALDH1A1 (0.38) | CLK4ALDH1A1LMNAPTGS2MAPK1 | |
| SCHEMBL15332139 | 0.81 | KMT2A (0.45) | ALDH1A1MEN1HTTKMT2AKDM4E | |
| SCHEMBL15331583 | 0.81 | TYR (0.40) | ALDH1A1LMNAPTGS2MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |