Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956063 | 0.95 | HPGD (0.70) | HPGDMAPTHTTTSHRKDM4E | |
| SCHEMBL29952571 | 0.84 | HPGD (0.50) | HPGDMAPTHTTKDM4EGAA | |
| SCHEMBL15331013 | 0.82 | HPGD (0.52) | HPGDTSHRKDM4EALDH1A1GAA | |
| SCHEMBL15331058 | 0.81 | LMNA (0.50) | HPGDHTTTSHRADRA2AADRA2B | |
| SCHEMBL29953044 | 0.81 | SMYD3 (0.47) | HPGDMAPTHTTKDM4EALDH1A1 | |
| SCHEMBL29955473 | 0.81 | ALDH1A1 (0.50) | HPGDMAPTHTTKDM4EALDH1A1 | |
| SCHEMBL8470131 | 0.81 | HPGD (0.41) | HPGDMAPTHTTADRA2AADRA2B | |
| SCHEMBL2562943 | 0.80 | ALDH1A1 (0.46) | HPGDHTTTSHRADRA2AADRA2B | |
| SCHEMBL15332624 | 0.80 | HPGD (0.54) | HPGDMAPTHTTTSHRALDH1A1 | |
| SCHEMBL2557678 | 0.78 | LMNA (0.47) | HPGDHTTTSHRADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |