Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954062 | 0.95 | HPGD (0.62) | HPGDKDM4ESMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL2562943 | 0.81 | ALDH1A1 (0.46) | HPGDKDM4ESMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL15331058 | 0.79 | LMNA (0.50) | HPGDSMN1; SMN2ALDH1A1KMT2AHTT | |
| SCHEMBL29952571 | 0.79 | HPGD (0.50) | HPGDKDM4EKMT2AMAPTHTT | |
| SCHEMBL15331013 | 0.78 | HPGD (0.52) | HPGDKDM4ESMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL8185048 | 0.77 | KMT2A (0.62) | HPGDSMN1; SMN2ALDH1A1KMT2AHTT | |
| SCHEMBL29955473 | 0.77 | ALDH1A1 (0.50) | HPGDKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL29953044 | 0.77 | SMYD3 (0.47) | HPGDKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL29957566 | 0.76 | HPGD (0.55) | HPGDSMN1; SMN2ALDH1A1KMT2APOLB | |
| SCHEMBL8470131 | 0.76 | HPGD (0.41) | HPGDKDM4ESMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |