Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 16/20 | 0.59 |
| ▸ | NPC1 | O15118 | 15/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.59 |
| ▸ | MAPT | P10636 | 10/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | TP53 | P04637 | 4/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | PPARG | P37231 | 1/20 | 0.59 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.59 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10297868 | 0.82 | NPC1 (0.76) | RAB9ANPC1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL10045300 | 0.75 | RAB9A (0.65) | RAB9ANPC1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL299974 | 0.75 | NPC1 (1.00) | RAB9ANPC1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL827403 | 0.74 | RAB9A (0.67) | RAB9ANPC1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL26745365 | 0.73 | RAB9A (0.63) | RAB9ANPC1KDM4EMAPTSMN1; SMN2 | |
| Methane SCHEMBL28056221 | 0.72 | RAB9A (0.64) | RAB9ANPC1KDM4EMAPTSMN1; SMN2 | |
| Hydrogen Sulfide SCHEMBL28205214 | 0.72 | RAB9A (0.64) | RAB9ANPC1KDM4EMAPTSMN1; SMN2 | |
| Hydrogen Sulfide SCHEMBL16859912 | 0.72 | RAB9A (0.64) | RAB9ANPC1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL2998404 | 0.72 | KDM4E (0.63) | RAB9ANPC1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL2380254 | 0.72 | RAB9A (0.68) | RAB9ANPC1KDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |