Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 14/20 | 1.00 |
| ▸ | RAB9A | P51151 | 14/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 1.00 |
| ▸ | MAPT | P10636 | 7/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 1.00 |
| ▸ | TP53 | P04637 | 3/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 1.00 |
| ▸ | HPGD | P15428 | 3/20 | 1.00 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 1.00 |
| ▸ | PPARG | P37231 | 1/20 | 1.00 |
| ▸ | NCOA2 | Q15596 | 1/20 | 1.00 |
| ▸ | NCOA1 | Q15788 | 1/20 | 1.00 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10297868 | 0.87 | NPC1 (0.76) | NPC1RAB9AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL10045300 | 0.79 | RAB9A (0.65) | NPC1RAB9AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL827403 | 0.78 | RAB9A (0.67) | NPC1RAB9AKDM4EMAPTSMN1; SMN2 | |
| Hydrogen Sulfide SCHEMBL16859912 | 0.76 | RAB9A (0.64) | NPC1RAB9AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL10186730 | 0.76 | KDM4E (0.61) | NPC1RAB9AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL25165415 | 0.75 | RAB9A (0.59) | NPC1RAB9AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL290274 | 0.75 | RAB9A (0.59) | NPC1RAB9AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL7269898 | 0.75 | RAB9A (0.59) | NPC1RAB9AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL29954067 | 0.75 | RAB9A (0.59) | NPC1RAB9AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL19961704 | 0.73 | RAB9A (0.59) | NPC1RAB9AKDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118178687-A | Active targeting nano platform for near infrared imaging and preparation method and application thereof | 中国科学院长春应用化学研究所 | 2024-06-14 | — | — | CN | disclosed |
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |