Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALDH5A1 | P51649 | 2/20 | 0.44 |
| ▸ | ABAT | P80404 | 2/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955982 | 0.88 | ALDH1A1 (0.44) | ALDH1A1TDP1ALDH5A1ABATTRIM24 | |
| SCHEMBL6478595 | 0.88 | HPGD (0.44) | ALDH1A1HPGDMIFRAB9AKDM4E | |
| SCHEMBL20132284 | 0.87 | CYP17A1 (0.45) | ALDH1A1TDP1ALDH5A1ABATTRIM24 | |
| SCHEMBL11999997 | 0.85 | CA12 (0.43) | ALDH1A1HPGDMIFRAB9AKDM4E | |
| SCHEMBL29953638 | 0.84 | BRAF (0.43) | ALDH1A1MIFRAB9AKDM4EHDAC1 | |
| SCHEMBL29956714 | 0.84 | PDK1 (0.44) | ALDH1A1MIFRAB9AKDM4EHDAC1 | |
| SCHEMBL20748365 | 0.83 | KDM4E (0.52) | ALDH1A1TDP1ALDH5A1ABATTRIM24 | |
| SCHEMBL5164739 | 0.82 | SMN1; SMN2 (0.44) | ALDH1A1HPGDMIFRAB9AKDM4E | |
| SCHEMBL2031546 | 0.81 | KCNMA1 (0.54) | HPGDSMN1; SMN2NPC1MAPTGAA | |
| SCHEMBL18002664 | 0.81 | NPC1 (0.45) | MIFRAB9AKDM4EHDAC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |