Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18587301 | 1.00 | PDK2 (0.42) | PDK2XDHMAPTPOLBHPGD | |
| SCHEMBL1348419 | 0.81 | NQO1 (0.46) | MAPTHPGDKAT6AMEN1KMT2A | |
| SCHEMBL27192103 | 0.80 | KMT2A (0.44) | PDK2XDHMAPTPOLBHPGD | |
| SCHEMBL12537785 | 0.78 | MCL1 (0.46) | PDK2MAPTMEN1KMT2ALMNA | |
| SCHEMBL29887229 | 0.78 | FYN (0.34) | MAOAMAOBFFAR1 | |
| SCHEMBL23673443 | 0.78 | FYN (0.34) | MAOAMAOBFFAR1 | |
| SCHEMBL1676909 | 0.78 | LTA4H (0.43) | PDK2MAPTKAT6AMEN1KMT2A | |
| SCHEMBL29958075 | 0.78 | LTA4H (0.43) | PDK2MAPTKAT6AMEN1KMT2A | |
| SCHEMBL8416 | 0.77 | ALDH1A1 (0.44) | PDK2POLBKAT6AKMT2AALDH1A1 | |
| SCHEMBL29587748 | 0.77 | ALDH1A1 (0.44) | PDK2POLBKAT6AKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |