Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1676909 | 1.00 | LTA4H (0.43) | LTA4HKAT6AKMT2APDK2MEN1 | |
| SCHEMBL12537785 | 0.93 | MCL1 (0.46) | LTA4HKMT2APDK2MEN1MCL1 | |
| SCHEMBL29953890 | 0.86 | LTA4H (0.43) | LTA4HKAT6AKMT2APDK2MEN1 | |
| SCHEMBL1348419 | 0.86 | NQO1 (0.46) | LTA4HKAT6AKMT2AMEN1FFAR1 | |
| SCHEMBL3787854 | 0.81 | LTA4H (0.44) | LTA4HKMT2AMEN1CA12CA1 | |
| SCHEMBL2212307 | 0.80 | LTA4H (0.46) | LTA4HKAT6AKMT2APDK2MEN1 | |
| SCHEMBL23673443 | 0.79 | FYN (0.34) | CA1CA2FFAR1 | |
| SCHEMBL9945993 | 0.79 | MCL1 (0.43) | LTA4HMCL1CA12CA1CA2 | |
| SCHEMBL8405356 | 0.79 | LTA4H (0.43) | LTA4HKMT2APDK2MEN1MCL1 | |
| SCHEMBL29955018 | 0.79 | LTA4H (0.43) | LTA4HKMT2APDK2MEN1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |