Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956006 | 0.88 | GAA (0.45) | NPC1LMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL408195 | 0.83 | NPY2R (0.47) | KMT2ANPC1LMNAHTTSMN1; SMN2 | |
| SCHEMBL29952726 | 0.82 | ALDH1A1 (0.49) | KMT2ALMNASMN1; SMN2PTGS2ALDH1A1 | |
| SCHEMBL1308951 | 0.82 | ALDH1A1 (0.49) | KMT2ALMNASMN1; SMN2PTGS2ALDH1A1 | |
| SCHEMBL4799859 | 0.81 | ALDH1A1 (0.42) | KMT2AHTTSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL4802706 | 0.81 | RAPGEF4 (0.39) | KMT2ANPC1LMNAHTTSMN1; SMN2 | |
| SCHEMBL29956135 | 0.81 | UTS2R (0.43) | KMT2ALMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL992209 | 0.81 | ACHE (0.42) | KMT2ALMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL29952320 | 0.80 | ALDH1A1 (0.46) | KMT2APTGS2ALDH1A1GAACA1 | |
| SCHEMBL4797196 | 0.78 | ALDH1A1 (0.50) | KMT2ANPC1LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |