Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 7/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18550296 | 1.00 | LIPE (0.53) | LIPEALOX5ALDH1A1MEN1NPC1 | |
| SCHEMBL29957511 | 0.88 | LIPE (0.53) | LIPEALOX5ALDH1A1MEN1NPC1 | |
| SCHEMBL539890 | 0.83 | LIPE (0.54) | LIPEALOX5MEN1NPC1RAB9A | |
| SCHEMBL29953350 | 0.83 | LIPE (0.68) | LIPEALOX5RAB9ASMN1; SMN2LMNA | |
| SCHEMBL29950569 | 0.83 | LIPE (0.54) | LIPEALOX5MEN1NPC1RAB9A | |
| SCHEMBL5433420 | 0.83 | LIPE (0.68) | LIPEALOX5RAB9ASMN1; SMN2LMNA | |
| SCHEMBL12180347 | 0.82 | DRD2 (0.56) | ALOX5ALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL29825561 | 0.81 | LIPE (0.53) | LIPEALOX5LMNACYP1A2PTGS1 | |
| SCHEMBL1711426 | 0.81 | LIPE (0.53) | LIPEALOX5LMNACYP1A2PTGS1 | |
| SCHEMBL6500766 | 0.80 | LIPE (0.59) | LIPEALOX5ALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |