Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | HTR2B | P41595 | 2/20 | 0.51 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL149599 | 0.79 | KDM1A (0.58) | HTR2AHTR2CHTR2BSLC6A3KDM1A | |
| SCHEMBL29957178 | 0.79 | HTR2C (0.50) | HTR2AHTR2CHTR2BKDM1ARCOR1 | |
| SCHEMBL1722128 | 0.77 | MAOB (0.48) | HTR2AHTR2CHTR2BSLC6A3SLC6A2 | |
| SCHEMBL29954166 | 0.77 | MAOB (0.48) | HTR2AHTR2CHTR2BSLC6A3SLC6A2 | |
| SCHEMBL1781688 | 0.77 | MAOB (0.48) | HTR2AHTR2CHTR2BSLC6A3SLC6A2 | |
| SCHEMBL29955006 | 0.75 | HTR2C (0.55) | HTR2AHTR2CHTR2BSLC9A1KDM1A | |
| SCHEMBL31172459 | 0.73 | HTR2A (0.58) | HTR2AHTR2CHTR2BSLC9A1SLC6A3 | |
| SCHEMBL12875538 | 0.73 | HTR2A (0.58) | HTR2AHTR2CHTR2BSLC9A1SLC6A3 | |
| SCHEMBL5521413 | 0.73 | HTR2C (0.62) | HTR2AHTR2CHTR2BSLC9A1SLC6A3 | |
| SCHEMBL7090511 | 0.73 | HTR2C (0.62) | HTR2AHTR2CHTR2BSLC9A1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |