Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 6/20 | 0.55 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.54 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.43 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | IAPP | P10997 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23018201 | 0.82 | ERN1 (0.57) | ERN1TRIM24TRIM33CA1CA2 | |
| SCHEMBL11439324 | 0.78 | CA2 (0.45) | CA1CA2LMNATHRBBLM | |
| SCHEMBL28298267 | 0.78 | ALDH1A1 (0.56) | ERN1TRIM24TRIM33CA1CA2 | |
| SCHEMBL16470058 | 0.78 | TDP1 (0.42) | ERN1TRIM24TRIM33CA1CA2 | |
| Salicyladehyde SCHEMBL9437422 | 0.77 | TRIM24 (0.82) | ERN1TRIM24TRIM33CA1CA2 | |
| SCHEMBL16119586 | 0.76 | ALDH1A1 (0.45) | ERN1TRIM24TRIM33CA1CA2 | |
| SCHEMBL28873592 | 0.76 | ERN1 (0.52) | ERN1TRIM24TRIM33CA1CA2 | |
| SCHEMBL7877994 | 0.76 | KDM4E (0.43) | ERN1LMNAMEN1THRBBLM | |
| SCHEMBL15009404 | 0.74 | SCN5A (0.46) | ERN1LMNAMEN1THRBBLM | |
| SCHEMBL3098499 | 0.74 | ERN1 (0.36) | ERN1TRIM24TRIM33CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |