Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.41 |
| ▸ | MMP9 | P14780 | 3/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 5/20 | 0.40 |
| ▸ | CA9 | Q16790 | 5/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL408195 | 0.91 | NPY2R (0.47) | NPY2RCA12CA9CA2CA1 | |
| SCHEMBL29956006 | 0.89 | GAA (0.45) | MMP2MMP9NPY2RCA12CA9 | |
| SCHEMBL29956135 | 0.81 | UTS2R (0.43) | LMNASMN1; SMN2ALDH1A1MAPTCNR2 | |
| SCHEMBL992209 | 0.81 | ACHE (0.42) | LMNASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL4799859 | 0.81 | ALDH1A1 (0.42) | MMP2CA12CA9CA2CA1 | |
| SCHEMBL4802706 | 0.81 | RAPGEF4 (0.39) | MMP2MMP9NPY2RCA12CA9 | |
| SCHEMBL29951226 | 0.79 | HTT (0.46) | NPY2RLMNASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL3271450 | 0.79 | AR (0.56) | CA12CA9CA2CA1LMNA | |
| SCHEMBL4797196 | 0.79 | ALDH1A1 (0.50) | LMNASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL29952766 | 0.79 | ALDH1A1 (0.48) | CA12CA9CA2LMNAMCOLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |