Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | UTRN | P46939 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7891367 | 1.00 | PIK3CA (0.50) | PIK3CANPC1RAB9APOLBKDM4E | |
| SCHEMBL7898012 | 0.90 | PIK3CA (0.48) | PIK3CANPC1RAB9APOLBKDM4E | |
| SCHEMBL29957899 | 0.90 | PIK3CA (0.48) | PIK3CANPC1RAB9APOLBKDM4E | |
| SCHEMBL14684624 | 0.83 | RAB9A (0.42) | PIK3CANPC1RAB9APOLBKDM4E | |
| SCHEMBL128647 | 0.82 | AGPAT2 (0.56) | PIK3CANPC1RAB9APOLBKDM4E | |
| SCHEMBL7892974 | 0.81 | LCK (0.52) | PIK3CANPC1RAB9APOLBKDM4E | |
| SCHEMBL23287676 | 0.81 | PIK3CA (0.51) | PIK3CANPC1RAB9APOLBKDM4E | |
| SCHEMBL13257845 | 0.81 | PIK3CA (0.51) | PIK3CANPC1RAB9APOLBKDM4E | |
| SCHEMBL14951188 | 0.78 | ENPP2 (0.43) | NPC1RAB9AFFAR2MAPTHDAC6 | |
| SCHEMBL9883987 | 0.78 | FBP1 (0.52) | PIK3CANPC1RAB9APOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |