Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | ITGAL | P20701 | 1/20 | 0.30 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.30 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10059031 | 0.85 | ALDH1A1 (0.36) | CES1ALDH1A1HDAC1HDAC8HDAC6 | |
| SCHEMBL10058185 | 0.84 | ALDH1A1 (0.36) | ALDH1A1HDAC1HDAC8HDAC6PTPN1 | |
| SCHEMBL20595653 | 0.80 | ALOX15 (0.35) | ALOX15TSHRKDM4EACMSDTDP1 | |
| SCHEMBL16014086 | 0.72 | BACE1 (0.39) | CES1 | |
| SCHEMBL15464396 | 0.71 | ALDH1A1 (0.50) | ALDH1A1HDAC1HDAC8HDAC6PTPN1 | |
| SCHEMBL18335237 | 0.70 | CES1 (0.49) | ALOX15TSHRKDM4EACMSDTDP1 | |
| SCHEMBL159215 | 0.70 | — | — | |
| SCHEMBL1816453 | 0.70 | — | — | |
| SCHEMBL27833977 | 0.69 | HCAR2 (0.38) | ALOX15TSHRKDM4EACMSDTDP1 | |
| SCHEMBL1807276 | 0.69 | CES1 (0.45) | ALOX15TSHRKDM4EACMSDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |