Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | KMO | O15229 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27038787 | 0.82 | ALDH1A1 (0.46) | TSHRFBP1ALDH1A1 | |
| SCHEMBL29954319 | 0.80 | ALOX15 (0.35) | ALOX15TSHRKDM4EACMSDTDP1 | |
| SCHEMBL20595599 | 0.74 | CYP1A2 (0.47) | KDM4EFBP1ALDH1A1 | |
| SCHEMBL24498384 | 0.72 | ALDH1A1 (0.50) | ALDH1A1 | |
| SCHEMBL16014086 | 0.72 | BACE1 (0.39) | CES1 | |
| SCHEMBL18335237 | 0.70 | CES1 (0.49) | ALOX15TSHRKDM4EACMSDTDP1 | |
| SCHEMBL1816453 | 0.70 | — | — | |
| SCHEMBL159215 | 0.70 | — | — | |
| SCHEMBL1807276 | 0.69 | CES1 (0.45) | ALOX15TSHRKDM4EACMSDTDP1 | |
| SCHEMBL20928818 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4558468-A2 | NITRIFICATION INHIBITING HETEROCYCLES | Corteva Agriscience LLC (US) | 2025-05-28 | — | — | EP | disclosed |
| WO-2024020529-A2 | NITRIFICATION INHIBITING HETEROCYCLES | CORTEVA AGRISCIENCE LLC (US) | 2024-01-25 | — | — | WO | disclosed |
| US-11465997-B2 | Synthesis of disorazoles and analogs thereof as potent anticancer agents | WILLIAM MARSH RICE UNIVERSITY (US) | 2022-10-11 | — | — | US | disclosed |
| US-20210155616-A1 | SYNTHESIS OF DISORAZOLES AND ANALOGS THEREOF AS POTENT ANTICANCER AGENTS | WILLIAM MARSH RICE UNIVERSITY (US) | 2021-05-27 | — | — | US | disclosed |
| US-20210155616-A1 | SYNTHESIS OF DISORAZOLES AND ANALOGS THEREOF AS POTENT ANTICANCER AGENTS | WILLIAM MARSH RICE UNIVERSITY (US) | 2021-05-27 | — | — | US | disclosed |
| EP-3641891-A1 | SYNTHESIS OF DISORAZOLES AND ANALOGS THEREOF AS POTENT ANTICANCER AGENTS | William Marsh Rice University (US) | 2020-04-29 | — | — | EP | disclosed |
| WO-2018237178-A1 | SYNTHESIS OF DISORAZOLES AND ANALOGS THEREOF AS POTENT ANTICANCER AGENTS | WILLIAM MARSH RICE UNIVERSITY (US) | 2018-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11465997-B2 | Synthesis of disorazoles and analogs thereof as potent anticancer agents | CD47, DUT, CD99 | ALOX15 2165/4885TSHR 3984/4885KDM4E 1977/4885 |
| US-20210155616-A1 | SYNTHESIS OF DISORAZOLES AND ANALOGS THEREOF AS POTENT ANTICANCER AGENTS | CD47, DUT, CD99 | ALOX15 2165/4885TSHR 3984/4885KDM4E 1977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.