Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | OXTR | P30559 | 1/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15330399 | 0.87 | ALDH1A1 (0.37) | KDM4EALDH1A1SIGMAR1KIF11MAPT | |
| SCHEMBL29952180 | 0.84 | ALDH1A1 (0.42) | KDM4EALDH1A1MAPTNPSR1 | |
| SCHEMBL2563069 | 0.84 | MAPK14 (0.41) | KDM4EALDH1A1MAPT | |
| SCHEMBL15331780 | 0.83 | ALDH1A1 (0.34) | SCN9ATDP2KDM4EALDH1A1AHR | |
| SCHEMBL15329462 | 0.83 | PTGS2 (0.45) | KDM4EALDH1A1MAPTNPSR1NPC1 | |
| SCHEMBL17290703 | 0.83 | SCN9A (0.44) | SCN9ATDP2SCN5AKDM4EALDH1A1 | |
| SCHEMBL29954930 | 0.83 | MEN1 (0.42) | SCN9ATDP2SCN5AKDM4EALDH1A1 | |
| SCHEMBL15331430 | 0.82 | SMN1; SMN2 (0.41) | TDP2ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL15331788 | 0.81 | SMN1; SMN2 (0.47) | TDP2KDM4EALDH1A1MAPTNPSR1 | |
| SCHEMBL29954023 | 0.80 | CSF1R (0.42) | KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |