Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | S100A4 | P26447 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957133 | 1.00 | ALDH1A1 (0.50) | ALDH1A1LMNASERPINE1NOTUMGAA | |
| SCHEMBL2556830 | 1.00 | ALDH1A1 (0.50) | ALDH1A1LMNASERPINE1NOTUMGAA | |
| SCHEMBL2555004 | 0.86 | TDP1 (0.59) | ALDH1A1SERPINE1NOTUMGAATDP1 | |
| SCHEMBL2558968 | 0.83 | SERPINE1 (0.54) | ALDH1A1LMNASERPINE1NOTUMGAA | |
| SCHEMBL29954516 | 0.80 | ALDH1A1 (0.69) | ALDH1A1LMNASERPINE1NOTUMGAA | |
| SCHEMBL2559422 | 0.80 | ALDH1A1 (0.69) | ALDH1A1LMNASERPINE1NOTUMGAA | |
| SCHEMBL29956907 | 0.80 | ALDH1A1 (0.69) | ALDH1A1LMNASERPINE1NOTUMGAA | |
| SCHEMBL22099636 | 0.79 | NOTUM (0.53) | ALDH1A1NOTUMMEN1KMT2AKDM4E | |
| SCHEMBL23850795 | 0.76 | LMNA (0.65) | ALDH1A1LMNAGAATDP1MAPT | |
| SCHEMBL23850888 | 0.76 | LMNA (0.65) | ALDH1A1LMNAGAATDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |