SCHEMBL29954473

SCHEMBL29954473

[C-]#[N+]c1cccc(Cl)c1F

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CFD P00746 1/20 0.35
CYP1A2 P05177 2/20 0.35
CYP2A6 P11509 2/20 0.35
TSHR P16473 2/20 0.33
LMNA P02545 1/20 0.33
IDO1 P14902 1/20 0.33
KAT2B Q92831 1/20 0.33
TAAR1 Q96RJ0 1/20 0.32
HCAR1 Q9BXC0 1/20 0.31
GAA P10253 1/20 0.31
PTGES2 Q9H7Z7 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
KMT2A Q03164 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL377007 0.76 TSHR (0.42) CYP1A2CYP2A6TSHRLMNAIDO1
SCHEMBL29957142 0.76 TSHR (0.42) CYP1A2CYP2A6TSHRLMNAIDO1
SCHEMBL2829059 0.76 CES2 (0.38)
SCHEMBL29953266 0.75
SCHEMBL653876 0.75
Hydrochloric Acid SCHEMBL3291195 0.74 TSHR (0.41) CYP1A2CYP2A6TSHRLMNAIDO1
SCHEMBL320817 0.74
SCHEMBL29957886 0.74 MPL (0.37) IDO1HCAR1ALDH1A1TDP1
Hydrochloric Acid SCHEMBL8436823 0.73 TSHR (0.45) CYP1A2CYP2A6TSHRLMNAIDO1
SCHEMBL1642170 0.73 ACHE (0.37) CYP1A2CYP2A6TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed