Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.50 |
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | HTR2B | P41595 | 3/20 | 0.50 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 3/20 | 0.40 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL149599 | 0.79 | KDM1A (0.58) | HTR2CHTR2AHTR2BKDM1ARCOR1 | |
| SCHEMBL29954593 | 0.79 | HTR2A (0.51) | HTR2CHTR2AHTR2BKDM1ARCOR1 | |
| SCHEMBL29953893 | 0.77 | KDM1A (0.52) | HTR2CHTR2AHTR2BKDM1A | |
| SCHEMBL15329847 | 0.77 | KDM1A (0.52) | HTR2CHTR2AHTR2BKDM1A | |
| SCHEMBL1722128 | 0.77 | MAOB (0.48) | HTR2CHTR2AHTR2BKDM1ARCOR1 | |
| SCHEMBL1781688 | 0.77 | MAOB (0.48) | HTR2CHTR2AHTR2BKDM1ARCOR1 | |
| SCHEMBL29954166 | 0.77 | MAOB (0.48) | HTR2CHTR2AHTR2BKDM1ARCOR1 | |
| SCHEMBL29955006 | 0.75 | HTR2C (0.55) | HTR2CHTR2AHTR2BKDM1ARCOR1 | |
| SCHEMBL19444237 | 0.73 | HTR2A (0.56) | HTR2CHTR2AHTR2BGRIA4KDM1A | |
| SCHEMBL13272292 | 0.73 | HTR2A (0.56) | HTR2CHTR2AHTR2BGRIA4KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |