Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5449273 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2CYP11B1CYP11B2KDM4ELMNA | |
| SCHEMBL15070002 | 0.74 | SMN1; SMN2 (0.44) | SMN1; SMN2 | |
| SCHEMBL5328437 | 0.72 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNA | |
| SCHEMBL50791 | 0.71 | GAA (0.39) | — | |
| SCHEMBL248285 | 0.69 | — | — | |
| SCHEMBL19919573 | 0.68 | SMN1; SMN2 (0.41) | SMN1; SMN2 | |
| SCHEMBL8681619 | 0.68 | — | — | |
| SCHEMBL21042654 | 0.67 | SMN1; SMN2 (0.56) | SMN1; SMN2CYP11B1CYP11B2KDM4ELMNA | |
| SCHEMBL2996694 | 0.67 | TSHR (0.35) | KDM4ELMNACYP2C19 | |
| SCHEMBL2790791 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100143805-A1 | NITROXIDES FOR LITHIUM-ION BATTERIES | CIBA CORPORATION (NY) | 2010-06-10 | — | — | US | disclosed |
| EP-2122739-A1 | NITROXIDES FOR LITHIUM-ION BATTERIES | BASF SE (DE) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008110466-A1 | NITROXIDES FOR LITHIUM-ION BATTERIES | BASF SE (CH) | 2008-09-18 | — | — | WO | disclosed |
| US-6664353-B2 | Compounds providing stable free radical-mediated polymerization processes which yield polymers having low polydispersity at enhanced rates of polymerization and enhanced monomer to polymer conversions | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-12-16 | — | — | US | disclosed |
| US-20030125494-A1 | Heterocyclic alkoxyamines as regulators in controlled radical polymerization processes | NESVADBA PETER (CH) | 2003-07-03 | — | — | US | disclosed |
| US-6479608-B1 | Heterocyclic alkoxyamines as regulators in controlled radical polymerization processes | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100143805-A1 | NITROXIDES FOR LITHIUM-ION BATTERIES | OGG1, NOX4, NQO1 | SMN1; SMN2 3538/4885CYP11B1 574/4885CYP11B2 354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.