Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.46 |
| ▸ | LCK | P06239 | 3/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955834 | 0.84 | TYR (0.43) | ERN1LCKCES2ALDH1A1CA12 | |
| SCHEMBL29953767 | 0.82 | CA12 (0.57) | ERN1LCKEGFRCES2ALDH1A1 | |
| SCHEMBL3388426 | 0.82 | CA12 (0.57) | ERN1LCKEGFRCES2ALDH1A1 | |
| SCHEMBL17825629 | 0.80 | ERN1 (0.42) | ERN1ALDH1A1TSHRKDM4ETDP1 | |
| SCHEMBL5087817 | 0.80 | CES2 (0.45) | ERN1CES2ALDH1A1KDM4ETDP1 | |
| SCHEMBL15088224 | 0.80 | MAPT (0.42) | ERN1ALDH1A1MAPTGAAKDM4E | |
| SCHEMBL28451382 | 0.78 | KDM4E (0.43) | LCKEGFRCES2ALDH1A1CA12 | |
| SCHEMBL14289910 | 0.78 | SRC (0.50) | ERN1ALDH1A1MAPTGAAKDM4E | |
| SCHEMBL5209251 | 0.78 | ERN1 (0.60) | ERN1CES2CA12CA9GAA | |
| SCHEMBL36835 | 0.76 | ERN1 (0.61) | ERN1EGFRALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |